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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BRF1
All Species:
13.64
Human Site:
S614
Identified Species:
23.08
UniProt:
Q92994
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92994
NP_001510.2
677
73840
S614
G
E
A
L
L
P
S
S
P
T
L
G
A
E
P
Chimpanzee
Pan troglodytes
XP_510208
819
88957
S756
G
E
A
L
L
P
S
S
P
T
L
G
A
E
P
Rhesus Macaque
Macaca mulatta
XP_001098066
599
65136
P543
S
P
A
L
R
A
E
P
A
R
P
Q
A
V
L
Dog
Lupus familis
XP_548005
637
70371
E581
S
P
P
A
L
G
A
E
A
V
R
P
A
A
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFK2
676
73781
S613
G
E
A
L
L
L
S
S
P
A
L
G
A
E
P
Rat
Rattus norvegicus
NP_001100231
686
74096
S623
G
E
A
L
L
L
N
S
P
A
L
G
A
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_421405
681
75256
A619
E
E
V
T
F
P
N
A
P
A
E
A
S
N
I
Frog
Xenopus laevis
NP_001088063
660
73751
E601
K
K
V
A
L
E
Q
E
V
I
N
E
P
E
S
Zebra Danio
Brachydanio rerio
NP_956183
693
76806
L620
K
K
R
T
A
A
A
L
F
T
P
S
M
T
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650616
662
73627
Q606
S
K
A
A
D
V
E
Q
A
E
T
K
P
A
V
Honey Bee
Apis mellifera
XP_623775
648
73504
T592
D
M
E
I
S
D
I
T
E
S
T
L
S
R
M
Nematode Worm
Caenorhab. elegans
NP_495526
759
84015
A650
I
G
A
K
K
L
A
A
L
N
E
V
K
N
V
Sea Urchin
Strong. purpuratus
XP_794011
768
83924
Q683
T
V
R
E
G
P
A
Q
K
T
A
K
L
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P29056
596
66888
A540
T
K
T
V
D
A
A
A
A
I
G
L
M
S
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
86.4
82.7
N.A.
89.8
81.6
N.A.
N.A.
78.1
72.5
65.9
N.A.
42.5
43.4
32.4
46.3
Protein Similarity:
100
80
87
85.9
N.A.
93.3
86
N.A.
N.A.
87
84.7
77.6
N.A.
59.6
61.7
50
60.1
P-Site Identity:
100
100
20
13.3
N.A.
86.6
80
N.A.
N.A.
20
13.3
6.6
N.A.
6.6
0
6.6
26.6
P-Site Similarity:
100
100
20
20
N.A.
86.6
86.6
N.A.
N.A.
40
20
20
N.A.
13.3
26.6
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
22
8
22
36
22
29
22
8
8
43
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
15
8
0
0
0
0
0
0
0
0
8
% D
% Glu:
8
36
8
8
0
8
15
15
8
8
15
8
0
43
0
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
29
8
0
0
8
8
0
0
0
0
8
29
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
8
0
0
8
0
0
15
0
0
0
0
8
% I
% Lys:
15
29
0
8
8
0
0
0
8
0
0
15
8
0
0
% K
% Leu:
0
0
0
36
43
22
0
8
8
0
29
15
8
0
8
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
15
0
15
% M
% Asn:
0
0
0
0
0
0
15
0
0
8
8
0
0
15
0
% N
% Pro:
0
15
8
0
0
29
0
8
36
0
15
8
15
0
36
% P
% Gln:
0
0
0
0
0
0
8
15
0
0
0
8
0
0
0
% Q
% Arg:
0
0
15
0
8
0
0
0
0
8
8
0
0
8
0
% R
% Ser:
22
0
0
0
8
0
22
29
0
8
0
8
15
8
8
% S
% Thr:
15
0
8
15
0
0
0
8
0
29
15
0
0
8
0
% T
% Val:
0
8
15
8
0
8
0
0
8
8
0
8
0
8
22
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _